Veterinary Biochemistry

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Veterinary Biochemistry
Department of Veterinary Biochemistry was created on 23rd December, 2004 as per the Registrar notification vide memo no. AA/RG-193/04/05/9836-9896 dated 23/12/2004. The department was  attached with Department of Animal Physiology, prior to its bifurcation. 
UG Courses
# Course No. Course Title Course Credit Syllabus
1 VPB-2 * Veterinary Biochemistry 3(2 + 1)
* courses are compulsory
Masters Courses
# Course No. Course Title Course Credit Syllabus
1 VBC-601 * CHEMISTRY OF ANIMAL CELL 2(2 + 0)
2 VBC-602 * TECHNIQUES IN BIOCHEMISTRY 2(0 + 2)
3 VBC-603 * APPLICATIONS OF GENOMICS AND PROTEOMICS IN MOLECULAR BIOLOGY 2(2 + 0)
4 VBC-604 * BIOCHEMISTRY OF BIOMOLECULES: CARBOHYDRATES LIPIDS AND MEMBRANE’S STRUCTURE 2(2 + 0)
5 VBC-605 * ENZYME CATALYSIS, KINETICS, INHIBITION AND REGULATION 2(2 + 0)
6 VBC-606 * METABOLISM-I: CARBOHYDRATES AND LIPIDS 2(2 + 0)
7 VBC-607 METABOLISM–II: NUCLEIC ACIDS AND AMINO ACIDS 2(2 + 0)
8 VBC-608 METABOLISM–III: INTEGRATION AND REGULATION 2(2 + 0)
9 VBC-609 CENTRAL DOGMA AND PROTEIN FUNCTION 2(2 + 0)
10 VBC-610 CLINICAL BIOCHEMISTRY OF ANIMALS 3(2 + 1)
11 VBC-611 BIOCHEMICAL BASIS OF DISEASES OF DOMESTIC ANIMALS 2(2 + 0)
12 VBC-612 ENDOCRINOLOGY AND REPRODUCTIVE BIOCHEMISTRY 2(2 + 0)
13 VBC-613 BIOCHEMICAL BASIS OF ANIMAL PRODUCTION 3(2 + 1)
* courses are compulsory
PhD Courses
# Course No. Course Title Course Credit Syllabus
1 VBC-701 * ADVANCES IN BIOCHEMISTRY OF RUMINANT DISORDERS 2(2 + 0)
2 VBC-702 * ADVANCES IN ENZYMOLOGY 2(2 + 0)
3 VBC-703 * ADVANCES IN CLINICAL BIOCHEMISTRY 2(0 + 2)
4 VBC-704 * MEMBRANE DYNAMICS AND SIGNAL TRANSDUCTION IN ANIMAL CELL 2(2 + 0)
5 VBC-705 * METHODS IN PROTEIN ANALYSIS 3(2 + 1)
6 VBC-706 * NUTRITIONAL BIOCHEMISTRY 2(2 + 0)
7 VBC-707 * ADVANCES IN INTERMEDIARY METABOLISM 2(2 + 0)
8 VBC-708 * ENDOCRINE CONTROL OF FUEL METABOLISM 2(2 + 0)
9 VBC-709 * DIAGNOSTIC ENZYMOLOGY - I 2(2 + 0)
10 VBC-710 * DIAGNOSTIC ENZYMOLOGY - II 2(2 + 0)
11 VBC-711 * BIOCHEMISTRY OF DEVELOPMENT AND DIFFERENTIATION 2(2 + 0)
12 VBC-712 * ADVANCES IN TECHNIQUES IN BIOCHEMISTRY 2(0 + 2)
13 VBC-713 * ADVANCES IN MINERAL AND VITAMIN METABOLISM AND RELATED DISEASES 2(2 + 0)
14 VBC-790 * SPECIAL PROBLEM 2(0 + 2)
* courses are compulsory
Projects
    • Central Council for Research in Ayurvedic Sciences (Ministry of Ayush, Govt. of India) sponsored project on "Acute and Ninety days repeated dose (Sub-chronic) oral toxicity studies of coded formulation Ayush-PTK", project cost Rs.13.14 Lakh
    • Central Council for Research in Ayurvedic Sciences (Ministry of Ayush, Govt. of India) sponsored project on "Evaluation of Neuroprotective and Antioxidant Effects of Vasantakusumakara rasa in a rat Model of Type II diabetes neuropathy", project cost Rs.21.88 Lakh
    • AAU sponsored project on "Development of cost-effective oral vaccine against necrotic enteritis", project cost Rs.4 Lakh
    • AAU sponsored project on "Development of climate resilient goat production through assisted reproductive technology", project cost Rs.4 Lakh
    • ASTEC, ASSAM sponsored project on "Development of a Nano zinc fortified herbal mix for increased productivity in Goat", project cost Rs.4.70 Lakh
    • Central Council of Research in Ayurvedic Sciences sponsored project on "Toxicity Studies and Evaluation of Anti-inflammatory and Anti-arthritic activity of Shunthi guggulu (Triphala shodhita) in Rats", project cost Rs.25.27940 Lakh
    • NER-BPMC sponsored project on "Promoting advance research and capacity building in biotechnology & allied disciplines through manpower training, mentoring and sharing of infrastructure developed under the Advanced Level State Biotech Hub",
    • ASTEC sponsored project on "Development of a Nano zink fortified herbal mix for increased productivity in goats", project cost Rs.470000.00 Lakh
    • AAU sponsored project on "Development of a Pheromone based spray for enhancing reproductive efficiency of Dairy Cattle of Assam", project cost Rs.4 Lakh
    • DBT, New Delhi sponsored project on "Validation and field testing of DIVA tests developed in ADMaC Phase-I project forsurveillance of brucellosis in North Eastern region of India", project cost Rs.27.17 Lakh
    • DBT, New Delhi sponsored project on "Development, evaluation and validation of peptide-based iELISA for the zoonoticdiseases, (1) Brucellosis and (2)Coxiellosis (Q-fever).", project cost Rs.40.22 Lakh
    • Department of Biotechnology, Govt of India sponsored project on "An Integrated Approach to Explore and Exploit the Innate and Adaptive Immune Response in Indigenous Duck Breeds of North Eastern and South India", project cost Rs.95 Lakh
    • DBT Govt of India sponsored project on "An Integrated Approach to Explore and Exploit the Innate and Adaptive Immune Response in Indigenous Duck Breeds of North Eastern and South India", project cost Rs.49.00 Lakh
    • DBT sponsored project on "Development of Nanoparticle or Microparticle Adjuvanted Subunit Oral Vaccine against Poultry Salmonellosis", project cost Rs.75 Lakh implemented in 2016.
    • DBT sponsored project on "Development of Nanoparticle or Microparticle Adjuvanted Subunit Oral Vaccine against Poultry Salmonellosis", project cost Rs.75 Lakh implemented in 2016. (PI/Co-PI/Associated Scientist : Dr. Shantanu Tamuly)
    • DBT , New Delhi sponsored project on "Role of Plant as a Modifier of Rumen to Reduce Methane Production and Improve Productivity in Small Animals", project cost Rs.36.26 Lakh implemented in 2014. (PI/Co-PI/Associated Scientist : Dr. Rita Nath)
    • Department of Biotechnology, Govt of India sponsored project on "Designing , Synthesis and Characterization of Antimicrobial Peptides", project cost Rs.49 Lakh implemented in 2013.
    • ASTEC, Assam sponsored project on "Baseline values of blood profile of Doom pigs of Assam", project cost Rs.1.99 Lakh implemented in 2013. (PI/Co-PI/Associated Scientist : Dr. Rita Nath)
    • DBT, Goivt of India sponsored project on "Designing , Synthesis and Characterization of Antimicrobial Peptides", project cost Rs.53 Lakh implemented in 2013. (PI/Co-PI/Associated Scientist : Dr. Dhruba Jyoti Kalita)
    • NPFR, AAU sponsored project on "Molecular Fingerprints of Mitochondrial DNA for indigenous Livestock Species of Assam", project cost Rs.6.72 Lakh implemented in 2013. (PI/Co-PI/Associated Scientist : Dr. Dhruba Jyoti Kalita)
    • DBT-AAU Centre sponsored project on "Comparative evaluation of whole outer membrane protein of Pasteurella multocida adjuvanted with calcium phosphate nanoparticles and polylactide-co-gly", project cost Rs.8 Lakh implemented in 2012.
    • DBT-AAU Centre sponsored project on "Comparative evaluation of whole outer membrane protein of Pasteurella multocida adjuvanted with calcium phosphate nanoparticles and polylactide-co-glycolide (PLG) microparticles as a vaccine candidate against swine pasteurellosis", project cost Rs.8 Lakh implemented in 2012. (PI/Co-PI/Associated Scientist : Dr. Shantanu Tamuly)
Achivements

  • Ø  A combination of polymerase chain reaction (PCR) with restriction fragment length polymorphism
    (RFLP) and nucleotide sequencing is the most preferred and efficient method for characterization of different
    species, in terms of detection power and applicability to large scale screening. The present study was carried out
    with the aim of developing the molecular fingerprint of the mitochondrial 16S rRNA gene of Cattle, Buffalo and
    Yak. Blood samples were collected randomly from ten different animals of each species for mitochondrial DNA
    extraction. The extracted DNA was used for the amplification of the 16S rRNA gene using universal primers.
    The size of the amplified products was 600bp. RFLP studies were carried out by digesting the amplicons
    using restriction enzymes viz. AluI, HinfI and HaeIII. The resulting RFLP pattern could easily identify and
    differentiate each of the species. Sequencing of the amplicons in all three species was carried out to confirm the
    variations at nucleotide level. Sequence analysis of the 16S rRNA gene using MEGA4 software and also PCRRFLP
    revealed that the 16S rRNA gene can be used as a good candidate for a molecular marker

  • Emergence
    of antibiotic resistance microorganism is a common problem in our country. Antibiotic
    resistant organism is a serious concern to veterinary and medical practices as
    well as animal food producers. To fight with antibiotics resistance organisms
    and for safe food consumption alternative group to replace some conventional
    antibiotic is the need of the hour.    Antimicrobial
    peptides are effective components of host defense and was explored as possible alternative
    to conventional antibiotics.     Vast array of endogenous peptide antibiotic are produced by
    epithelial lining of the different organ and involve in continuous anti germ
    warfare. Different tissues from indigenous animals were collected , RNA was extracted and cDNA  was synthesized. All these cDNA were used for amplification of different AMP genes using specific primer. The PCR products were cloned and sequenced were analyzed and predicted for different peptides. The amino acid sequences of these peptides were used as template for synthesis of different animicrobial peptides and antimicrobial activities of these peptides were evaluated in representative gram positive and gram negative bacteria.